Research has been ongoing now for years as scientists have tried to determine whether stem cells from adult tissues have the same capabilities and potential as embryonic stem cells. Studies are constantly revealing new information and it is hoped that therapeutic applications will be developed from both sources. The question, however, perhaps remains: which source holds the advantage?
Researchers have demonstrated that any mature adult cell has the potential to turn into the equivalent of an embryonic stem cell. By Lori J. Date January 29, April 16,
Stem cells obtained from human embryos seem to offer the best chance of new therapies, because unlike other stem cells they have the ability to morph into almost any type of tissue. But researchers complain that political roadblocks are keeping them from determining the full potential of these cells. Six years ago, President Bush limited federally funded research to about 20 viable lines of cells that had been extracted from embryos prior to August 9, The stem cell community has repeatedly called for the restrictions to be lifted, charging that the designated cell colonies have been compromised or corrupted and that failure to ease the ban is hobbling U.
Since the discovery of human embryonic stem cells, scientists have had high hopes for their use in treating a wider variety of diseases because they are pluripotent, which means they are capable of differentiating into one of many cell types in the body. However, the acquisition of human embryonic stem cells from an embryo can cause the destruction of the embryo, thus raising ethical concerns. Inresearchers introduced an alternative to harvesting embryonic stem cells called induced pluripotent stem iPS cells.
The results have been published in the journal Cell Cycle. Stem cells are specialized, undifferentiated cells that can divide and have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, they serve as a sort of internal repair system in many tissues, dividing essentially without limit to replenish other cells.
Successful scale-up of human embryonic stem cell production in a stirred microcarrier culture system A. Sartore 1B. Paulsen 1R.
Not a MyNAP member yet? Register for a free account to start saving and receiving special member only perks. Human embryonic stem cells hES cells are primitive undifferentiated cells that can self-renew or differentiate into most or all cell types found in the adult human body Edwards, ; Gardner, Differentiation is the process whereby an unspecialized cell acquires specialized features, such as those of a heart, liver, or muscle cell.
ATCC offers a complete system of tri-lineage-capable neural progenitor cells NPCslineage marker-labeled NPCs, as well as expansion and differentiation media, for generating neurons, astrocytes, and oligodendrocytes. These cells are multipotent; they can renew themselves and can differentiate to a variety of specialized cells found in the blood. ATCC offers media and supplements, easy-to-use cell dissociation reagents, and hassle-free cryopreservation media optimized for culturing stem cells.