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High-dose iodized oil transcatheter arterial chemoembolization for patients with large hepatocellular carcinoma. In this study, we used cDNA expression microarray containing genes related to carcinoma to analyze genes that are differentially expressed in human Hepatoma cell line HLE. Several genes related to cell cycle regulators, growth regulators were abundantly up-regulated in our HCC samples. Genes differentially expressed between hepatoma cell line HLE and normal liver tissues generated by AtlasImage software Version 1. Microarray techniques have been developed in this conditions[ 23 ]. GAPDH was used as an internal control. Quantitative monitoring of gene expression patterns with a complementary DNA microarray.

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Although human genome projects have generated a large-scale sequence data for millions of genes, the biological functions of such genes remain to be deciphered.

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The comparison results analyzed by AtlasImage software showed that there were 30 genes changed, 22 up-regulated and 8 down-regulated in Hepatoma cell line HLE versus normal liver tissues. Inhibition of binding of fibronectin to matrix assembly sites by anti-integrin alpha 5 beta 1 antibodies. Tumor development and progression involves a cascade of genetic alterations.

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